The TRPC4AP antibody from Wuhan Fine Biotech Co., Ltd. is a Mouse Monoclonal antibody to TRPC4AP. This antibody recognizes Homo Sapiens, and Human antigen. The TRPC4AP antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Substrate-specific adapter of a DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1